EMBL researchers have designed a computational method to jointly analyse multiple types of molecular data from patients in order to identify molecular signatures that distinguish individuals. The method is called Multi-Omics Factor Analysis (MOFA), and was published in Molecular Systems Biology. MOFA could be particularly useful for understanding cancer development, improving diagnosis and suggesting new directions for persona...

Constructing biological tissues, such as skin, muscle, or bone, in customised shapes is now one step closer. Researchers at EMBL have succeeded in guiding the folding and thus shape of tissues with optogenetics: a technique to control protein activity with light. Nature Communications published their results, with implications for regenerative medicine. The changing of tissue shapes in an embryo is essential for healthy development...

A type of HIV drug currently being tested works in an unusual way, scientists in the Molecular Medicine Partnership Unit, a collaboration between EMBL and Heidelberg University Hospital, have found. They also discovered that when the virus became resistant to early versions of these drugs, it did not do so by blocking or preventing their effects, but rather by circumventing them. The study, published online in Science, presents the most detailed ...

As the bioimaging revolution gives scientists ever-more detailed views on the inner workings of cells, there is growing demand for public infrastructure to store, share and link the massive datasets produced using high-resolution imaging techniques. Complementing large-scale, EMBL-led, intergovernmental initiatives such as Euro-BioImaging, the EMBL-EBI has expanded its EMPIAR data service to accommodate new high-resolution imaging modalities such...