Grafted organoids provide insight into neurological disorders
Many neurological disorders—Alzheimer’s, schizophrenia, autism, even depression—have lagged behind in new therapies. Because the brain is so complex, it can be difficult to discover new drugs and even when a drug is promising in animal models, it often doesn’t work for humans. Scientists are aiming to change that with stem cell technology by taking skin cells from a patient and turning those cells into neurons.
Using AI to detect heart disease
Heart disease is the leading cause of death for both men and women, according to the Centers for Disease Control and Prevention (CDC). In the U.S., one in every four deaths is a result of heart disease, which includes a range of conditions from arrhythmias, or abnormal heart rhythms, to defects, as well as blood vessel diseases, more commonly known as cardiovascular diseases.
An augmented reality microscope for cancer detection
Applications of deep learning to medical disciplines including ophthalmology, dermatology, radiology, and pathology have recently shown great promise to increase both the accuracy and availability of high-quality healthcare to patients around the world. Google has also published results showing that a convolutional neural network is able to detect breast cancer metastases in lymph nodes at a level of accuracy comparable to a trained pathologist.
Add-on pad can make defibrillators more effective
The Zfib team of Rice senior bioengineering students has created an add-on for automated external defibrillators – aka AEDs – that literally punches through the skin to help deliver a jolt to a person in cardiac arrest. With the help of advisers Eric Richardson, a Rice bioengineering lecturer, and Dr. Mehdi Razavi, a cardiologist at Texas Heart Institute, the students developed a needle-laden pad that can be pressed through both ...
Computer algorithm helps develop ultra-powerful peptides
During the past several years, many strains of bacteria have become resistant to existing antibiotics, and very few new drugs have been added to the antibiotic arsenal. To help combat this growing public health problem, some scientists are exploring antimicrobial peptides — naturally occurring peptides found in most organisms. Most of these are not powerful enough to fight off infections in humans, so researchers are trying to come up ...
Caffeine helps develop gels for drug delivery
Caffeine is well-known for its ability to help people stay alert, but a team of researchers at MIT and Brigham and Women’s Hospital has now come up with a novel use for this chemical stimulant — catalysing the formation of polymer materials. Using caffeine as a catalyst, the researchers have devised a way to create gummy, biocompatible gels that could be used for drug delivery and other medical applications.
Teaching computers how to analyse brain cells
In the early days of neuroscience research, scientists painstakingly stained brain cells and drew by hand what they saw in a microscope. Fast forward to 2018 and machines may be able to learn how to do that work. According to a study in Cell, it may be possible to teach machines how to pick out features in neurons and other cells that have not been stained or undergone other damaging treatments. The study was partially funded by the NINDS, p...
Augmented reality app may aid patients with Parkinson’s
It’s appropriate that during Parkinson’s Awareness Month, a team of Rice University seniors will show how augmented reality may help patients with the disease. Six Rice engineering students have designed an iPhone app to help patients overcome a symptom known as “freezing,” in which the legs temporarily refuse to follow the brain’s command to lift and move forward.
OCS lung system for double transplants receives FDA PMA
TransMedics, Inc. has announced that the FDA approved its Pre-Market Approval Application (PMA) for the Organ Care System (OCS) Lung platform for the standard double lung transplant indication. The INSPIRE Trial that supported the PMA was the first and largest controlled clinical organ preservation trial ever in lung transplantation and was conducted at 21 leading international academic institutions.
Iontophoretic contact lens technology receives new patent
EyeGate Pharmaceuticals, Inc. has announced that the United States Patent and Trademark Office (USPTO) has issued the Company a patent covering the utility of its iontophoretic contact lens. The U.S. patent entitled “Iontophoretic Contact Lens” was issued on the 10th April, 2018. “The issuance of this new patent represents a significant milestone in the development of our proprietary iontophoretic contact lens,” said ...