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Wellcome Trust Sanger Institute

Wellcome Trust Sanger Institute Articles

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Medical
18th May 2018
Gonorrhoea surveillance study maps antibiotic resistance across Europe

The first European-wide genomic survey of gonorrhoea has mapped antibiotic resistance in this sexually transmitted disease throughout the continent. Researchers at The Centre for Genomic Pathogen Surveillance (CGPS), the Wellcome Sanger Institute, the European Centre for Disease Prevention and Control, and their collaborators also showed that using DNA sequencing data they could accurately determine antibiotic resistance and identify incorrect la...

Medical
11th July 2017
Researchers establish mechanism controlling cell division

Researchers at the Francis Crick and Gurdon Institutes have pinpointed the mechanism that activates a key point in embryonic development. This could help scientists develop treatments for diseases where the cell cycle is disrupted, such as cancer. The earliest stages of development in many animals happen very quickly. There is a rapid expansion in the number of cells that make up the embryo structure known as the blastula.

Medical
31st May 2017
Identifying the genetic cause of childhood cancer

Scientists have identified a genetic mutation that causes a childhood kidney cancer called Wilms' tumour. The research revealed how loss of control over the number of chromosomes in a cell can lead to cancer. Researchers looked at families with a rare genetic syndrome called mosaic variegated aneuploidy (MVA) to try to identify mutations that might be linked to Wilms' tumour.

Medical
19th May 2017
Resistance to malaria linked to human red blood cell receptors

Researchers have discovered that protection from the most severe form of malaria is linked with natural variation in human red blood cell genes. A study from the Wellcome Trust Sanger Institute, the Wellcome Trust Centre for Human Genetics and their collaborators has identified a genetic rearrangement of red blood cell glycophorin receptors that confers a 40 per cent reduced risk from severe malaria.

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