Nanorobots could swim through blood to deliver drugs

27th July 2015

Siobhan O'Gorman

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Someday, treating patients with nanorobots could become standard practice to deliver medicine specifically to parts of the body affected by disease. However, merely injecting drug-loaded nanoparticles might not always be enough to get them where they need to go. In the ACS journal, Nano Letters, scientists are reporting the development of new nanoswimmers that can move easily through body fluids to their targets.

Nanorobots could have many benefits for patients. For example, they could be programmed to specifically wipe out cancer cells, which would lower the risk of complications, reduce the need for invasive surgery and lead to faster recoveries. It’s a burgeoning field of study with early-stage models currently in development in laboratories. However, one of the challenges to making these robots work well is getting them to move through body fluids, which are like molasses to something as small as a nanorobot. Bradley J. Nelson, Salvador Pané, Yizhar Or and colleagues wanted to address this problem.

The researchers strung together three links in a chain about as long as a silk fibre is wide. One segment was a polymer, and two were magnetic, metallic nanowires. They put the tiny devices in a fluid even thicker than blood. When the researchers applied an oscillating magnetic field, the nanoswimmer moved in an S-like, undulatory motion at the speed of nearly one body length per second. The magnetic field can also direct the swimmers to reach targets.